Ive run Adaware, Spybot SD, SuperAntiSpyware, and AVG antispyware and they all come back clean. Ive run ATH cleaner and Vundofix. ComboFix comes back clean in safe mode but when I reboot in normal mode, core.cache.dsk is still there and Combofix cant delete it and all my attempts to manually delete it have failed. Every time I reboot it makes IE my default browser (I use Firefox), and I get IE popups every 5 mins or so when I'm browsing, most of the time the popups hang and dont actually connect to anything. I'm at my wits end here, any help would be greatly appreciated.
attached are my current Combofix and HJT logs