This Add or Remove Programs entry corresponds to a program that is either malware, installs malware, or is bundled with malware.
It is advised that you uninstall this program from your computer due to the above reasons. If this program gave you the option to not install the malware or adware during setup, and you chose that option, then it should be safe to leave the program installed. Please note that not all programs listed here will actually be uninstalled when you attempt to do so. In situations like this it is advised that you ask follow the steps in this guide in order to receive help cleaning your computer.
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Yahoo! Assistant, originally called 3721 Internet Assistant, is a browser help object for Internet Explorer. It is know to change Internet Explorer settings and make itself difficult to remove. More information can be found here.