BleepingComputer.com: Cleaning Registry errors

Hi. I'm new. Hope I'm in the right topic place...
For months now I get a start-up error message fretting that the system can't find "C:\Program Files\NOS\bin\getPlus_HelperSvc.exe" which, according to BleepingComputer's information, is a downloader for Adobe updates, and is not necessary (at least for start-ups). I've done full system searches for this file with no luck, but if I do a search for the file name as an entry within files, I get many listings for it within the Registry (over a hundred last time I checked). I've tried using Glary Utilities Registry Cleaner, which always finds it as an error, and cleans it---but only one entry at a time, apparently, since if I run it again, it finds it again. And again and... Any suggestions? I'm using Windows XP, with REGEDIT 4, but I fear to use that to simply delete the entries, not knowing what I might screw up.

Bleeping Computer DOES NOT recommend the use of registry cleaners/optimizers for a several reasons:

Registry cleaners can damage the registry by using aggressive cleaning routines. Many users (including some Staff Members) have reported problems after using registry cleaning tools - to include those tools released by Microsoft. This can cause your system to become unbootable.

Registry cleaners generally don't do anything significant for your system. This topic discusses it in greater detail than we could address here: http://www.windowsbbs.com/showthread.php?t=61015 Although the topic discusses the XP registry, the concepts there apply to all other versions of Windows.

Not all registry cleaners create a backup of your registry before making changes. If the changes prevent the system from booting/logging in, then there's no backup to restore in order to regain functionality. A backup of the registry is essential BEFORE making any changes to the registry.