I believe that I had Ultimate Defender installed and I think I was pretty successful getting rid of it. One of UD's traits is that it wants to hijack your browser. I think the problems I am having are as a result of having UD on my machine. One file that I had was qewiyrui.exe, which would keep appearing. I was able to get rid of this one for good.
I have a problem where Windows Explorer crashes on startup and wants to send an error report. If I say yes or no, IE still exits basically rendering it useless. Since the Microsoft update wants to use IE, you basically can't do the update on demand. I can use Opera but I still seem to have the hijacking problem.
This is a relatively new machine and I would do a reformat if reqired, but would love not to have to!
Any ideas?