I just completed a removal of SpySheriff using the info from this site. I must say it was really great help. After following all the steps in the process, my system seems to be running properly again. I ran a Panda or McFee scan that indicated a problem identified as "c:\secure32.html". When I ran an HJT scan, this item did not appear. Since my system is running fine, I hesitated to post the log. A Google search supported the commentary about this being a virus/malware problem. But a search on this site returned no hits. So, my question is: DO I HAVE A PROBLEM? And if so, what do I do about it. I can readily get to the subject file using My Computer and/or searching. Why wouldn"t HJT pick this up?

Hijack this is an ennumerator.
It lists what is found in certain areas of the registry, or system files, in an easily accessible manner, so that those familiar with the use and reading of HijackThis logs, and windows programs, can determine what is infecting the machine, and how to remove it.

It is not a removal tool.
It will indeed remove the entries listed, but that does not cure the underlying problem.
The problem must be properly identified first, and cured, prior to removing the entries with HJT.
Otherwise you leave the infection, and remove the keys which are needed to identify and remove it .

Removing entries in HJT before the problem is properly identified, and correct removal instructions posted, can make the problem undetectable to other detection and removal tools.
Do not have HJT fix anything without consulting with someone with HijackThis logfile knowledge.

Hijack this should only be used to clean up the entries left behind, after you have properly removed the offending program, file, trojan, worm, hijacker etc.
And this usually requires help.

HJT could be picking it up, but the entry is unrecognizable to you.
That's why training in the use of HJT, is necessary.
If in doubt, post a HJT log to be examined.