Hello ilovesd90macs and welcome,
If Explorer crashes and you can't get to the start menu you can press
CTRL+ALT+DEL this will bring up the Task Manager click
New Task and type
explorer.exe this will restart explorer.
To delete the file, firstly, what is the file? is it a system file? Or is it a user created file?
If you want to delete the file using command prompt. use the
dir command to list all the directories in the location the prompt is pointing to. Then the
cd command to change directory i.e
cd Documents and settings. then the
del command. i.e
del random file.
If the file refuses to go quietly then you can use
Unlocker this tool will unlock the file from the process that is using the file and allow it to be deleted.