Well I can't seem to fix this myself I see lots of people come here for help so add me to the list I hope to save this machine without a full reinstall if possible.
Here is the hijack log.

Logfile of HijackThis v1.99.0
Scan saved at 13:26: VIRUS ALERT!, on 7/1/2008
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v7.00 (7.00.6000.16674)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\ANI\ANIWZCS2 Service\ANIWZCSdS.exe
C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
C:\Program Files\Grisoft\AVG Anti-Spyware 7.5\guard.exe
C:\Program Files\Softex\OmniPass\Omniserv.exe
C:\PROGRA~1\TRENDM~1\INTERN~2\PcCtlCom.exe
C:\PROGRA~1\TRENDM~1\INTERN~2\PcScnSrv.exe
C:\WINDOWS\system32\HPZipm12.exe
C:\WINDOWS\System32\svchost.exe
C:\PROGRA~1\TRENDM~1\INTERN~2\Tmntsrv.exe
C:\PROGRA~1\TRENDM~1\INTERN~2\TmPfw.exe
C:\PROGRA~1\TRENDM~1\INTERN~2\tmproxy.exe
C:\Program Files\Softex\OmniPass\OPXPApp.exe
C:\WINDOWS\system32\wscntfy.exe
C:\WINDOWS\Explorer.EXE
C:\windows\system\hpsysdrv.exe
C:\Program Files\Hewlett-Packard\Digital Imaging\Unload\hpqcmon.exe
C:\Program Files\Hewlett-Packard\HP Share-to-Web\hpgs2wnd.exe
C:\PROGRA~1\TRENDM~1\INTERN~2\pccguide.exe
C:\WINDOWS\system32\rundll32.exe
C:\Program Files\Grisoft\AVG Anti-Spyware 7.5\avgas.exe
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\SUPERAntiSpyware\SUPERAntiSpyware.exe
C:\WINDOWS\system32\rundll32.exe
C:\WINDOWS\System32\svchost.exe
c:\Program Files\Hewlett-Packard\HP Share-to-Web\hpgs2wnf.exe
C:\WINDOWS\system32\wuauclt.exe
C:\Documents and Settings\Owner\Desktop\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://us8.hpwis.com/
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://srch-us8.hpwis.com/
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = www.yahoo.com
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://www.yahoo.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://us.rd.yahoo.com/customize/ie/defaul...//www.yahoo.com
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Bar = http://us.rd.yahoo.com/customize/ie/defaul...rch/search.html
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://us.rd.yahoo.com/customize/ie/defaul...//www.yahoo.com
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.comcast.net/
R1 - HKCU\Software\Microsoft\Internet Explorer\SearchURL,(Default) = http://us.rd.yahoo.com/customize/ie/defaul...//www.yahoo.com
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Window Title = Windows Internet Explorer provided by Comcast
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyServer = :0
R3 - URLSearchHook: Yahoo! Toolbar - {EF99BD32-C1FB-11D2-892F-0090271D4F88} - C:\Program Files\Yahoo!\Companion\Installs\cpn2\yt.dll
O2 - BHO: (no name) - AutorunsDisabled - (no file)
O2 - BHO: (no name) - {06647158-359E-4D10-A8DE-E6145DA90BE9} - (no file)
O2 - BHO: UberButton Class - {5BAB4B5B-68BC-4B02-94D6-2FC0DE4A7897} - C:\Program Files\Yahoo!\Common\yiesrvc.dll
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre1.5.0_11\bin\ssv.dll
O3 - Toolbar: hp toolkit - {B2847E28-5D7D-4DEB-8B67-05D28BCF79F5} - C:\HP\EXPLOREBAR\HPTOOLKT.DLL
O4 - HKLM\..\Run: [hpsysdrv] c:\windows\system\hpsysdrv.exe
O4 - HKLM\..\Run: [CamMonitor] c:\Program Files\Hewlett-Packard\Digital Imaging\Unload\hpqcmon.exe
O4 - HKLM\..\Run: [Share-to-Web Namespace Daemon] c:\Program Files\Hewlett-Packard\HP Share-to-Web\hpgs2wnd.exe
O4 - HKLM\..\Run: [Recguard] C:\WINDOWS\SMINST\RECGUARD.EXE
O4 - HKLM\..\Run: [pccguide.exe] C:\PROGRA~1\TRENDM~1\INTERN~2\pccguide.exe
O4 - HKLM\..\Run: [nwiz] nwiz.exe /install
O4 - HKLM\..\Run: [d856b58b] rundll32.exe "C:\WINDOWS\system32\cqiboufl.dll",b
O4 - HKLM\..\Run: [!AVG Anti-Spyware] "C:\Program Files\Grisoft\AVG Anti-Spyware 7.5\avgas.exe" /minimized
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - HKCU\..\Run: [SUPERAntiSpyware] C:\Program Files\SUPERAntiSpyware\SUPERAntiSpyware.exe
O4 - HKCU\..\RunOnce: [CheckNetworkConnection] "C:\Program Files\Support.com\providerComcast\desktopdoctor.exe" /flow /flow=diagnosenetwork /trayclick=true /haveconfirmedwiring=true /haverenewed=true /haverestartedmodem=true /onrestart=true /havehealed=true /issuenumber=d9ace654-ae97-4a49-8a44-e99c1615692a
O6 - HKCU\Software\Policies\Microsoft\Internet Explorer\Restrictions present
O8 - Extra context menu item: &Yahoo! Search - file:///C:\Program Files\Yahoo!\Common/ycsrch.htm
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\OFFICE11\EXCEL.EXE/3000
O8 - Extra context menu item: Yahoo! &Dictionary - file:///C:\Program Files\Yahoo!\Common/ycdict.htm
O8 - Extra context menu item: Yahoo! &Maps - file:///C:\Program Files\Yahoo!\Common/ycmap.htm
O8 - Extra context menu item: Yahoo! &SMS - file:///C:\Program Files\Yahoo!\Common/ycsms.htm
O9 - Extra button: (no name) - AutorunsDisabled - (no file)
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.5.0_11\bin\ssv.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.5.0_11\bin\ssv.dll
O9 - Extra button: Yahoo! Services - {5BAB4B5B-68BC-4B02-94D6-2FC0DE4A7897} - C:\Program Files\Yahoo!\Common\yiesrvc.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~2\OFFICE11\REFIEBAR.DLL
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - %windir%\Network Diagnostic\xpnetdiag.exe (file missing)
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - %windir%\Network Diagnostic\xpnetdiag.exe (file missing)
O11 - Options group: [INTERNATIONAL] International*
O12 - Plugin for .spop: C:\Program Files\Internet Explorer\Plugins\NPDocBox.dll
O16 - DPF: {6414512B-B978-451D-A0D8-FCFDF33E833C} (WUWebControl Class) - http://update.microsoft.com/microsoftupdat...b?1187909607093
O16 - DPF: {6B75345B-AA36-438A-BBE6-4078B4C6984D} (HpProductDetection Class) - http://h20270.www2.hp.com/ediags/gmn2/inst...ctDetection.cab
O16 - DPF: {6E32070A-766D-4EE6-879C-DC1FA91D2FC3} (MUWebControl Class) - http://update.microsoft.com/microsoftupdat...b?1187909596546
O16 - DPF: {9600F64D-755F-11D4-A47F-0001023E6D5A} (Shutterfly Picture Upload Plugin) - http://web1.shutterfly.com/downloads/Uploader.cab
O16 - DPF: {E008A543-CEFB-4559-912F-C27C2B89F13B} (Domino Web Access 7 Control) - https://staff.luzerne.edu/dwa7W.cab
O21 - SSODL: WPDShServiceObj - {AAA288BA-9A4C-45B0-95D7-94D524869DB5} - C:\WINDOWS\system32\WPDShServiceObj.dll
O23 - Service: ANIWZCSd Service - Alpha Networks Inc. - C:\Program Files\ANI\ANIWZCS2 Service\ANIWZCSdS.exe
O23 - Service: Apple Mobile Device - Apple, Inc. - C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
O23 - Service: AVG Anti-Spyware Guard - GRISOFT s.r.o. - C:\Program Files\Grisoft\AVG Anti-Spyware 7.5\guard.exe
O23 - Service: Google Updater Service - Google - C:\Program Files\Google\Common\Google Updater\GoogleUpdaterService.exe
O23 - Service: InstallDriver Table Manager - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\11\Intel 32\IDriverT.exe
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: Softex OmniPass Service - Unknown - C:\Program Files\Softex\OmniPass\Omniserv.exe
O23 - Service: Trend Micro Central Control Component - Trend Micro Inc. - C:\PROGRA~1\TRENDM~1\INTERN~2\PcCtlCom.exe
O23 - Service: Trend Micro Protection Against Spyware - Trend Micro Inc. - C:\PROGRA~1\TRENDM~1\INTERN~2\PcScnSrv.exe
O23 - Service: Pml Driver HPH11 - HP - C:\WINDOWS\system32\HPHipm11.exe
O23 - Service: Pml Driver HPZ12 - HP - C:\WINDOWS\system32\HPZipm12.exe
O23 - Service: Trend Micro Real-time Service - Trend Micro Inc. - C:\PROGRA~1\TRENDM~1\INTERN~2\Tmntsrv.exe
O23 - Service: Trend Micro Personal Firewall - Trend Micro Inc. - C:\PROGRA~1\TRENDM~1\INTERN~2\TmPfw.exe
O23 - Service: Trend Micro Proxy Service - Trend Micro Inc. - C:\PROGRA~1\TRENDM~1\INTERN~2\tmproxy.exe

I have moved your Topic that includes a HijackThis log here to the Misplaced HJT Logs forum. You posted your log in a forum not intended for HijackThis logs analysis and probably missed the directions we provide to those who require assistance. We can only allow topics with such logs in the HijackThis Logs and Malware Removal forum. This restriction is to ensure you get the best help available, from those who specialize in malware anlaysis and removal. It also should prevent you from receiving ineffective or even potentially dangerous advice, whether well meaning or not.

Prior to posting a HJT log, we ask that you please read and follow all instructions in the pinned topic titled Preparation Guide For Use Before Posting A Hijackthis Log. Following the steps in this Guide will allow the HJT Team to quickly help you with specific fixes for what may remain on your system.

Please complete all the steps in the Guide. If you have performed some of them already, then just continue with the next. There are instructions for downloading and running Deckard's System Scanner (DSS) which will create a hijackthis log for you, or automatically download and install the most current version of HijackThis if it's not already installed on your computer.

Please note that it is important that Deckard's System Scanner be run and a log created while in normal mode. If you run it and create your log while in safe mode, you will be asked to redo it again properly. When you have completed those steps, start a new topic in the HijackThis Logs and Malware Removal forum as directed in the Guide to post a new log.

Please DO NOT post any more logs to this topic, or post a log again in the wrong forum.

The Misplaced HJT Logs forum is strictly a holding area where the BC Staff can assist you with preparations for and to properly post your log. If you have a question or encounter a problem in the Prep Guide, please do post back to this topic; that is what it is here for.

When your new HJT log is posted in the proper forum, please reply to this topic with a link to your new topic. Once that is done, a Member of the HJT Team will analyze your log and assist you with step by step instructions to clean your computer or otherwise advise what needs to be done.

Thanks for your cooperation and good luck.
The BC Staff/Animal