My computer froze while playing a game, I thought that Cool & Quiet may be responsible. In the past it has and shutting it off stopped the freezes. I went into the BIOS of my Asus A832-SLI Deluxe and disabled the feature. Upon restart, the computer froze with a flashing cursor on a black screen just before Vista was supposed to load. I tried re-enabling Cool & Quiet, but it happened again. I then tried to repair my OS with the install disc only to discover that the computer would not read the disc. It didn't spin or anything, the floppy drive didn't respond either. I also noticed, when I restarted the computer, the hard drives weren't being accessed. Until this is fixed, I cannot use the computer.
EDIT: Fixed it. I had no idea there was a difference between simply hitting the reset button and powering off then back on again.