Delete Remove Index.dat Files
Here's what you can do to automatically wipe out the index.dat files on a Windows 2000 Professional or a Windows XP Professional machine during each shutdown. This automatic method does not work on Windows XP Home edition but you will see how to do it manually.
Index.dat files keep a record of every website you have ever visited and the one in the Content.ie5 folder just keeps growing and growing. It's OK to delete the Index.dat files as Windows will created new empty files after rebooting.
Go to http://www.compu-docs.com/indexdat.htm for the full instructions. If you then scoot around that site some you'll find a lot of other goodies. This is not another of those freebie, "too good to be true" sites, it's a legitimate computer business in New Jersey with a great customer service philosophy.
Hope this helps some of you.